Tick-Borne Encephalitis
January 2010
What is Tick-Borne Encephalitis?
Tick-borne encephalitis (TBE) is a viral disease that causes swelling of the brain (encephalitis), swelling of the membrane around the brain and spinal cord (meningitis), and/or swelling of the spinal cord (myelitis). It is transmitted through the bite of an infected tick.
TBE is caused by a flavivirus within the tick borne complex. A related member, Powassan virus, can be found in Canada.
There are three sub-types:
- Central European TBE virus;
- Siberian TBE virus; and
- Far eastern TBE virus (previously known as Russian spring-summer encephalitis virus)
Depends on factors such as destination, activities, duration of trip, and time of year.
The risk is greater for travellers who:
- spend time walking, cycling, camping, or working in wooded or forested areas
- consume unpasteurized milk or milk products.
The risk is less for travellers who stay in urban areas and do not participate in outdoor activities
Depends on subtype of TBE:
- Central European TBE: 70-90% of cases are asymptomatic, with a case-fatality rate of less than 2%, and among those who recover there is lasting neurological damage of up to 30%;
- Siberian TBE: more frequently associated with chronic disease and has a case fatality rate of 2%-3%;
- Far eastern TBE: thought to be the most severe, with a case fatality rate between 20-40% and higher rates of neurological damage among those who recover, although this may be an artifact of case reporting;
Severity increases with age.
There is no specific treatment for TBE.
Treatment consists of supportive medical care.
Symptoms
- Usually take between 7 to 14 days to appear, but can take as long as 28 days.
- Take less time to appear if exposed through milk or milk products, i.e.: 3 to 4 days.
- Often present in two phases:
- in the first phase, symptoms are flu-like and include fever, malaise, headaches, nausea and vomiting.
- in second phase, symptoms involve the central nervous system and can include encephalitis (swelling of the brain), meningitis (swelling of the membrane around the brain and spinal cord), and/or myelitis (swelling of the spinal cord).
- In more severe cases, complications during the second phase may cause long term neurological damage or even death. Long-term effects can include:
- severe headaches
- memory loss
- lack of concentration
- decreased stamina
- depression
- loss of coordination
- tremors, and/or
- hearing impairment
Transmission
- TBE is spread through the bite of an infected tick, primarily of the Ixodes ricinus and Ixodes persulcatus species.
- Ticks that transmit TBE can be found particularly in woodlands and at woodland edges, in parks and where the countryside is moist and uncultivated, containing low brush and ground foliage.
- Ticks generally bite from April to November with peak biting activity in early and late summer (i.e.: May/June and September/October).
- TBE can also be transmitted through contaminated unpasteurized cow, sheep, or goat milk and milk products obtained from infected animals.
Where is Tick-Borne Encephalitis a concern?
- TBE is found across Europe and Asia, from eastern France to Northern China and Japan. The geographical “belt” stretches across Russian and south to Albania.
- Countries recently reporting higher incidence of TBE include; Austria, Czech Republic, Estonia, Germany, Hungary, Latvia, Lithuania, Poland, Russia, Slovenia, Sweden and Switzerland.
- A
map of countries and areas of risk for TBE is available from the website of the International Working Group on Tick-Borne Encephalitis.
Related Travel Health Notices
None.
Recommendations for Travellers
- Follow personal protective measures to avoid tick bites
- Cover up:
- Wear long-sleeved, tucked-in shirts, long pants, shoes (not sandals) or boots.
- Smoothly woven clothing makes it more difficult for ticks to attach.
- Tape the cuffs of your pants or tuck them inside your boots or shoes.
- Treat your clothing with permethrin.
- Permethrin isn't available in Canada, however, travel health clinics can advise you how to purchase permethrin and treat your clothing before or during your trip.
- Permethrin-treated clothing is effective for up to two weeks or six washings.
- Use arthropod repellent on exposed skin:
- Arthropod repellents that contain DEET are the most effective
- Use as directed by the manufacturer
- Do not apply to cuts, scrapes, abrasions or irritated skin
- Do not spray directly on your face
- Wash your hands after you apply repellent to avoid contact with your lips and eyes
- Do not use products that contain both repellent and sunscreen
- If you want to use sunscreen and an arthropod repellent with DEET, apply the sunscreen first. Let it soak into your skin for about 20 minutes, then apply repellent with DEET
- Wash off repellent at the end of the day, before you go to bed.
Additional information on avoiding arthropod bites…
- Follow personal protective measures after high-risk activities:
- Check your skin and clothes for ticks:
- Ticks do not always begin feeding immediately after they attach themselves although transmission of the virus usually occurs early in the feeding process.
- Common areas to find ticks include the hair-line, behind the ears, on elbows, the backs of knees, the groin and/or armpits.
- The bite is painless and is often not noticed.
- An adult tick that has finished feeding may be as large as a coffee bean. Immature ticks are considerably smaller.
- Carefully remove any ticks you find:
- Use tweezers or blunt curved forceps to remove ticks.
- Grasp the tick as close to the skin as possible and pull steadily upwards without twisting or jerking. This increases your chances of removing all of the tick.
- Do not use alcohol, matches or petroleum jelly (i.e. Vaseline) to remove ticks.
- Do not handle ticks with your bare hands.
- The bite site should be disinfected after tick removal and you should wash your hands with soap and water.
- The date of the tick bite and the start of any symptoms should be documented.
- If any symptoms occur within 28 days of the tick bite see a doctor, nurse or health care provider immediately.
- Consider getting vaccinated:
Travellers who may be at risk should consult a health care provider to discuss the benefits of getting vaccinated.
- Avoid unpasteurized milk and milk products.

Don't Forget…
- Consult a doctor, nurse or health care provider or visit a travel health clinic at least six weeks before you travel.
- What to do if you get sick when you are travelling.
- What to do if you get sick after you return to Canada.
- Know what vaccines you need and when to get them.
Other Related Information
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