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Text Equivalents - CCDR: Volume 40-19, December 18, 2014

Figure 1: Rates of reported cases of Hepatitis C in Canada by sex, CNDSS, 1991-2012

Year TOTAL rate per 100,000 MALE rate per 100,000 FEMALE rate per 100,000
1991 5.2 6.4 3.9
1992 15.6 20.2 10.9
1993 20.8 27.3 13.9
1994 32.0 41.3 22.2
1995 64.5 83.9 44.4
1996 53.6 68.6 38.1
1997 60.9 79.0 42.5
1998 66.9 88.9 45.0
1999 62.7 81.8 42.9
2000 57.8 73.7 38.3
2001 54.3 71.5 36.2
2002 50.9 67.2 34.5
2003 46.8 61.1 32.3
2004 45.2 59.0 30.9
2005 40.3 53.1 27.5
2006 36.9 48.1 25.5
2007 36.6 46.2 26.2
2008 35.8 45.7 25.5
2009 33.3 42.7 23.3
2010 31.1 40.2 21.6
2011 28.9 36.8 20.7
2012 29.3 36.8 21.5

Return to Figure 1: Rates of reported cases of Hepatitis C in Canada by sex, CNDSS, 1991-2012

Figure 2: Rates of reported cases of Hepatitis C in males in Canada by age group, CNDSS, 2005-2012

  Age group (years)
Year 10-14 15-19 20-24 25-29 30-39 40-59 60+
2005 0.6 6.8 33.2 56.7 83.9 101.0 21.8
2006 0.7 5.8 28.7 50.8 72.7 93.0 20.8
2007 0.3 6.7 29.0 50.6 68.0 88.1 22.2
2008 0.8 5.8 30.8 51.1 62.0 88.7 22.3
2009 0.5 5.0 27.8 50.2 61.1 81.5 20.4
2010 0.6 5.8 26.8 42.1 55.1 76.9 22.8
2011 0.3 6.0 23.8 42.6 50.7 67.2 24.6
2012 0.2 5.7 30.8 41.5 51.7 64.4 26.3

Return to Figure 2: Rates of reported cases of Hepatitis C in males in Canada by age group, CNDSS, 2005-2012

Figure 3: Rates of reported cases of Hepatitis C in females in Canada by age group, CNDSS, 2005-2012

  Age group (years)
Year 10-14 15-19 20-24 25-29 30-39 40-59 60+
2005 1.2 13.4 36.6 35.6 45.6 40.7 15.9
2006 0.6 12.1 30.4 40.8 39.4 38.1 14.7
2007 0.5 11.8 31.4 39.7 40.0 40.7 14.2
2008 0.9 12.9 33.7 38.1 40.5 37.7 14.6
2009 0.7 13.0 29.9 36.1 35.1 35.3 13.0
2010 0.5 9.1 29.4 33.5 32.1 33.1 12.0
2011 0.6 7.9 27.1 32.0 31.0 31.4 12.5
2012 0.3 10.0 33.0 38.2 32.3 29.9 12.7

Return to Figure 3: Rates of reported cases of Hepatitis C in females in Canada by age group, CNDSS, 2005-2012

Figure 4: Rates of reported cases of Hepatitis C in Canada by age group and sex, CNDSS, 2012

  Age group (years)
Sex 0-4 5-9 10-14 15-19 20-24 25-29 30-39 40-59 60+
Male 1.7 0.4 0.2 5.7 30.8 41.5 51.7 64.4 26.3
Female 2.0 0.6 0.3 10.0 33.0 38.2 32.3 29.9 12.7

Return to Figure 4: Rates of reported cases of Hepatitis C in Canada by age group and sex, CNDSS, 2012

Figure 1: Estimated prevalence of chronic HCV infection (per 100 population) in Canada from a back-calculation model

The prevalence of CHC per 100 population is estimated from the back-calculation model, stratifying data to every 5-year birth cohort according to the year of birth.  Each birth cohort is a demographically defined population. The overall CHC prevalence, approximately 0.64%, is estimated regardless of age and year of birth. CHC prevalence in persons born before 1949 has declined from approximately 1% to below the overall prevalence in the past 20 years. Persons born after 1965 show a trend of an increasing CHC prevalence reaching from below the overall prevalence to above it. CHC prevalence in persons born between 1950 and 1964 remained above the overall prevalence throughout the 20 year period.

Return to Figure 1: Estimated prevalence of chronic HCV infection (per 100 population) in Canada from a back-calculation model

Figure 1: HCV genotype distribution among cases of acute/recent HCV infection in British Columbia (2000-2013)

  HCV-1a HCV1b HCV-2a HCV-2b HCV-3a HCV-4 HCV 1+3 HCV mixed (other) HCV-6 %HCV genotype
All of BC 49.56 5.12 1.85 4.14 33.44 0.98 3.16 1.42 0.33  
VCHA 48.83 5.81 1.55 2.32 36.04 1.16 2.32 1.55 0.38 distribution
Rest of BC 49.85 4.85 1.97 4.85 32.42 0.9 3.48 1.36 0.3 2000-2013

Return to Figure 1: HCV genotype distribution among cases of acute/recent HCV infection in British Columbia (2000-2013)

Figure 2: Proportion of HCV genotype 1 and 3a among cases of acute/recent HCV infection in British Columbia: 2000-2013

  Percentage of total
Year British Columbia;HCV-3 British Columbia;HCV-1
2000 46 51
2001 23 51
2002 31 64
2003 25 64
2004 31 63
2005 24 63
2006 24 63
2007 36 49
2008 36 49
2009 32 57
2010 32 64
2011 34 61
2012 36 54
2013 28 64

Return to Figure 2: Proportion of HCV genotype 1 and 3a among cases of acute/recent HCV infection in British Columbia: 2000-2013

Figure 3: Phylogentic tree based on Hepatitis C virus E1 gene

Phylogenetic tree demonstrates the genetic relatedness of  different  Hepatitis C virus isolates. Sequences on the same vertical line are identical. The length of horizontal lines separating sequences or branches of sequences is proportional to the number of differences (measured in single nucleotides) between the sequences. There are red dots on 13 among over 40 different nucleotide sequences that, when present in different specimens, indicate statistically plausible transmission from the same source.

Return to Figure 3: Phylogentic tree based on Hepatitis C virus E1 gene