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Supplement

Canadian Recommendations for the Prevention and Treatment of Malaria Among International Travellers

Appendix II

Strength and Quality of Evidence Summary*

Category
Definition
Categories for the strength of each recommendation
A
Good evidence to support a recommendation for use.
B
Moderate evidence to support a recommendation for use.

C

Poor evidence to support a recommendation for or against use.

D

Moderate evidence to support a recommendation against use.
E
Good evidence to support a recommendation against use.
Categories for the quality of evidence on which recommendations are made
I
Evidence from at least one properly randomized, controlled trial.
II
Evidence from at least one well-designed clinical trial without randomization, from cohort or case-controlled analytic studies, preferably from more than one centre, from multiple time series, or from dramatic results in uncontrolled experiments.
III
Evidence from opinions or respected authorities on the basis of clinical experience, descriptive studies, or reports of expert committees.

*From Macpherson DW. Evidence-based medicine. CCDR 1994; 20:145-47.


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