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Canada Communicable Disease Report

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Volume: 26S2 - March 2000

2000 Canadian recommendations for the prevention and treatment of malaria among international travellers
prepared by the
COMMITTEE TO ADVISE ON TROPICAL MEDICINE AND TRAVEL (CATMAT)


APPENDIX II Strength and Quality of Evidence Summary Sheet*

Categories for the strength of each recommendation

CATEGORY

DEFINITION

A

Good evidence to support a recommendation for use.

B

Moderate evidence to support a recommendation for use.

C

Poor evidence to support a recommendation for or against use.

D

Moderate evidence to support a recommendation against use.

E

Good evidence to support a recommendation against use.

Categories for the quality of evidence on which recommendations are made

GRADE

DEFINITION

I

Evidence from at least one properly randomized, controlled trial.

II

Evidence from at least one well designed clinical trial without randomization, from cohort or case-controlled analytic studies, preferably from more than one centre, from multiple time series, or from dramatic results in uncontrolled experiments.

III

Evidence from opinions or respected authorities on the basis of clinical experience, descriptive studies, or reports of expert committees.

* From: Macpherson DW. Evidence-based medicine. CCDR 1994;20:145-47.

 

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