Current Projects

As part of our mandate, NLHI is continually developing and validating new technologies, protocols, and instrumentation that may potentially enable clinicians to monitor disease progression in HIV/AIDS patients in a more efficient and/or cost-effective manner. Some of the projects that NLHI has undertaken in the last 2 years include:

Multiplexed in vitro diagnostics

• Integrated solid-phase multiple immunoassays
• Immune-function markers (naive/memory cells)
• Evaluation of 1 and 2 laser multi-color technology
• Investigation of HIV Clade Characterization Assay

Single Platform Absolute Count Technology (SPT)

• Develop Quality Control (QC) system for SPT for Absolute Counting
• Intracellular cytokine quantitation
• Development of new guidelines for CD4 cells

Clinical Potential for Quantitative Fluoresence Measurement

• Development of new QC products for SPT
• Gating algorithms for naïve/memory cells
• Quantitative measurement of immune-status markers