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An Advisory Committee Statement (ACS)
National Advisory Committee on Immunization (NACI)
February 2014

Statement on the Booster for 4-6 year-olds for Protection against Pertussis

Summary Table of Information Contained in this NACI Statement

The following table highlights key information for immunization providers from the full National Advisory Committee on Immunization (NACI): Statement on the Booster for 4-6 year-olds for Protection against Pertussis .

For readers interested in the full PDF version of the Statement on the Booster for 4-6 year-olds for Protection against Pertussis , the document is available for downloading or viewing on the Government of Canada PublicationsExternal site Web site.

1. What

Children in Canada receive a booster dose of diphtheria (d or D), tetanus (T), acellular pertussis (ap or aP) and inactivated polio vaccine (IPV) - at 4-6 years of age through vaccines that contain combinations of these antigens. There are products with a lower concentration of pertussis antigen (ap) and others with a higher concentration of pertussis antigen (aP). Fewer adverse events (local immunization site reactions) are reported with Tdap-IPV. DTaP-IPV elicits a greater immune response to pertussis, however, the clinical significance of this is not known. Either DTaP-IPV or Tdap-IPV vaccines may be used for the 4- to 6-year-old booster in children. NACI does not preferentially recommend one vaccine over the other.

2. Who

Children 4-6 years of age who are scheduled to receive booster vaccines.

3. How

One dose of combined diphtheria, tetanus, acellular pertussis and inactivated polio vaccine product should be administered intramuscularly.

4. Why

Pertussis continues to occur in a cyclic pattern every 2-5 years, therefore ongoing protection is needed.